What is BioNuesis?What does BioNuesis contain?Is BioNuesis stable?
28th International Symposium on the Separation of Proteins, Peptides and Polynucleotides
September 21-24, 2008
Baden-Baden, Germany
2008 World Stem Cell Summit
September 22-23, 2008
Madison, WI USA
BioTech Forum
September 23-25, 2008
Copenhagen
Stem Cells, Cancer and Aging
September 29-October 4, 2008
Philadelphia, PA
ICSE 2008
September 30-October 2, 2008
Messe Frankfurt, Germany
Bioforum 2008
October 1-2, 2008
Milan, Italy
9th International Congress on Cell Biology
October 7-10, 2008
Seoul, Korea
BioTechnica
October 7-9, 2008
Hannover, Germany
3rd Annual Translational Stem Cell Research Conference
October 14-15, 2008
New York, NY USA
Training Program: Methods in Human Embryonic Stem Cell Research
October 14-18, 2008 (annually)
The Jackson Laboratory
Bar Harbor, ME
barbara.donovan@jax.org
Training Program: Introduction to Human Embryonic Stem Cell Culture Methods
November 3-5, 2008
WiCell Research Institute, University of Wisconsin
Madison, WI USA
Biotechnology Business Exchange 2008
December 8, 2008
London, UK
Training Program: Introduction to Human Embryonic Stem Cell Culture Methods
December 8-10, 2008
WiCell Research Institute, University of Wisconsin
Madison, WI USA
48th American Society of Cell Biology Annual Meeting
December 13-17, 2008
San Francisco, CA USA
Training Program: Essentials of Human Embryonic Stem Cell Culture Techniques
University of Minnesota Stem Cell Institute
Minneapolis, MN
January 12-14, 2009 (Quarterly)
firpo001@umn.edu
Short-Term Course in Human Embryonic Stem Cell Culture
January 12-16, 2009 (Semiannually)
Technion/Johns Hopkins University
Baltimore, MD USA
itskovitz@rambam.health.gov.il
Asia Pharma Expo 2009
January 22-24, 2009
Dhaka, Bangladesh
InformExUSA
January 27-30, 2009
San Francisco, CA
Drug Discovery Latin America
February 26-27, 2009
Rio de Janeiro, Brazil
Proteomic Forum 2009
March 29-April 2, 2009
Berlin, Germany
Training Program: Essentials of Human Embryonic Stem Cell Culture Techniques
University of Minnesota Stem Cell Institute
Minneapolis, MN
April 28-30, 2009 (Quarterly)
firpo001@umn.edu
ACHEMA 2009
May 11-15, 2009
Frankfurt, Germany
BIO International Convention
May 18-21, 2009
Atlanta, Georgia
12th Annual Conference of the BioSafety Association
June 15-17, 2009
Stockholm, Sweden
ISSCR 7th Annual Meeting
July 8-11, 2009
Barcelona, Spain
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August 31-September 3, 2009
Seoul, Korea
HUPO 2009 8th Annual World Congress
September 26-October 30, 2009
Toronto, Canada
Media Contact:
Eileen Naughton
Histogen, Inc.
Phone: 619-318-7821
enaughton@histogeninc.com
SAN DIEGO, September 22, 2008 - Histogen, Inc., a regenerative medicine company developing solutions based on the products of newborn fibroblasts, today launched BioNuesis™, the only soluble human extracellular matrix (ECM) developed as a culturing kit for stem cell growth. The kit was launched and is being exhibited at the 2008 World Stem Cell Summit taking place in Madison, Wisconsin.
Through its proprietary bioreactors, Histogen is uniquely capable of simulating the embryonic environment, creating products that are embryonic-like in nature without the utilization of embryonic stem cells. Products are developed by extracting the proteins and growth factors produced by these fibroblasts. In working with the unique liquid formulation, Histogen researchers identified the potential for the human soluble ECM in the field of stem cell research, as compared to currently available products.
"There is a significant need for an all-human ECM product that can support pluripotent huES cell expansion in culture, without the complications inherent with mouse tumor-derived ECM extracts that are still the best replacement for feeder-layer cells," Dr. Jeanne Loring, Director of the Center for Regenerative Medicine at Scripps Research Institute. "Histogen's technology may provide the solution and help accelerate both basic science and translational research using huES cells."
BioNuesis is the first product that provides a limitless source of the natural human ECM proteins, such as laminin, collagen type 4 and fibronectin, which are required to expand human ES cells to commercial-scale.
Because current products utilize non-human sources, and can even contain mouse viruses, stem cell therapies developed using these animal products are not likely to be approved by the FDA. The technology behind the BioNuesis research kit, soluble natural human ECM, offers a solution which will eventually facilitate translation of stem cell cures to the public.
The launch of BioNuesis marks the entrance of Histogen into the marketplace as a number of products based on Histogen's proprietary technology continue down the pipeline.
"Histogen is uniquely capable of utilizing every aspect of the liquid and solid created by the Company's proprietary technology process, and developing high-value, all-human products at a commercial scale," said Dr. Gail Naughton, CEO of Histogen. "We are excited to bring our first product to the stem cell research market, and look forward to launching products in the cosmeceutical and medical fields in the near future."
About Histogen
Histogen, launched in 2007, seeks to redefine regenerative medicine by developing a series of high- value products without the use of embryonic stem cells or animal products. Through Histogen's proprietary bioreactors that mimic the embryonic environment, newborn fibroblasts are encouraged to naturally produce the vital proteins and growth factors from which the company has developed its rich product portfolio. Histogen has two product families - Exceltrix™, Histogen's human Extracellular Matrix (ECM) and ReGenica™, Histogen's proprietary liquid formula. For more information, please visit http://www.histogeninc.com.
About the World Stem Cell Summit
The World Stem Cell Summit, to be held Sept. 22-23, 2008 at Madison's Alliant Center, is a gathering of scientists, company leaders, ethicists, investors and more from virtually everywhere stem-cell research is underway. The event will coincide with the 10-year anniversary of UW-Madison scientist James Thomson becoming the first to successfully isolate and culture human embryonic stem cells. For more information about the Summit, visit http://www.worldstemcellsummit.com
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