What is BioNuesis?What does BioNuesis contain?Is BioNuesis stable?
BioNuesis™ is a soluble all-human extracellular matrix kit, developed by Histogen, Inc. Through its proprietary bioreactors, Histogen is uniquely capable of simulating the embryonic environment, creating products that are embryonic-like in nature. By extracting the proteins and growth factors produced by these fibroblasts, Histogen has created the unique BioNuesis liquid formulation.
Cultured cells generally require exogenous proteins which can be coated to the growth vessel surface, and provide a means of cell attachment. Some cell types, including human embryonic stem cells, require specialized proteins which provide for adherence, but also support proliferation while maintaining a pluripotent phenotype.
The soluble human extracellular matrix proteins in BioNuesis provide an entirely human source of the ECM molecules laminin, fibronectin and collagen type IV, which have been shown to support human ES cell expansion, and which are also found in the murine tumor-derived ECM gels, such as MatriGel™. BioNuesis contains natural human laminin, fibronectin and collagen type IV in a ready-to-use format for cell culture applications.
For product usage information, applications and research, click here to view BioNuesis product information.
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